A calprotectin stool test may help determine whether you have an inflammatory or noninflammatory bowel condition. The information it provides may also eliminate the need for more invasive tests ...

Medically reviewed by Jay N. Yepuri, MD Inflammatory bowel disease (IBD) is a group of chronic (long-term) conditions that cause inflammation in the digestive tract, which includes the mouth, ...

Peripheral arthritis in people with Crohn’s disease also has a tie to HLA-B27, but it’s less strong. In this type of arthritis, there’s a very strong link to a rare HLA gene called HLA-DR103.

Crohn’s disease can affect your quality of life and impact your health outside of the disease itself. For example: You might need a permanent ostomy , which could lead to body image issues.

The study, titled "Noninvasive stool RNA test approximates disease activity in patients with Crohn’s disease," assessed 102 stool samples from 68 individuals, collected over multiple time points ...

More than half a million people in the United States live with Crohn’s disease. New guidelines from the American Gastroenterological Association recommend biomarkers found in blood and stool be ...

Medically reviewed by Jay N. Yepuri, MD Medically reviewed by Jay N. Yepuri, MD Crohn's disease flare-ups can occur due to internal or external triggers, which vary by person. Knowing your ...

Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn’s disease activity index: National Cooperative Crohn’s Disease Study. Gastroenterology 1976;70:439-444. Crossref ...

Upadacitinib, an oral selective Janus kinase (JAK) inhibitor, is under investigation for the treatment of Crohn’s disease. In two phase 3 induction trials (U-EXCEL and U-EXCEED), we randomly ...