Previously, end-to-end chromosomal fusion events and breakage were regarded as the prime initiator, but new work reveals that exonucleases first chew away at chromosomes with short telomeres. Carol ...

Notably, when PICH is missing, genetic errors are more likely to occur in non-centromeric regions of the DNA due to the breakage of UFBs, leading to dangerous chromosome rearrangements that can ...

Importantly, McClintock noted that the frequency and timing of variegation and chromosome breakage were linked. Today we also know that transposons constitute a large fraction of the DNA in some ...

Ds Genetic location on the short arm of chromosome 9 at which chromosomal breakage occurs. As A factor of unknown location (at least when McClintock was conducting her research) that impacts the ...

Notably, when PICH is missing, genetic errors are more likely to occur in non-centromeric regions of the DNA due to the breakage of UFBs, leading to dangerous chromosome rearrangements that can ...