The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

With a new mapping tool, Princeton engineers have revealed how a factory inside cells builds ribosomes, the machinery ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

The primary function of the nucleolus is as the site of ribosome-subunit biogenesis in eukaryotic cells. Nucleoli form at the end of mitosis around the tandemly repeated clusters of ribosomal DNA ...

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus.

The size of the nucleolus could determine how long a cell has before it dies—and the smaller, the better. By Darren Orf Published: Jan 06, 2025 8:00 AM EST. Zeferli // Getty Images.

The nucleus contains the cell's chromosomes, while the nucleolus houses the ribosomal DNA (rDNA). The nucleolus isolates rDNA, which encodes the RNA components of ribosomes, the protein-building ...

The nucleolus is the largest structure inside the cell's nucleus, key to cell growth and stress response. One of its main jobs is building ribosomes, which are the scaffolds that cells use to make ...

MIT biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus.

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...