Live-cell imaging demonstrates that a subset of neuroblastoma cells evades chemotherapy-induced death if they are in early G1 phase of the cell cycle at the time of drug treatment and have ...

New research shows how cells carrying damaged DNA can sidestep cell cycle checkpoints that should prevent them from dividing ...

In a wholly new approach to cancer treatment, Northwestern University biomedical engineers have doubled the effectiveness of chemotherapy in animal experiments.

Background: The International Adjuvant Lung Cancer Trial (IALT) demonstrated that adjuvant cisplatin-based chemotherapy improves the 5-year survival rate of patients with completely resected non-small ...

“The p53 protein can be activated by DNA damage and functions as a transcription factor to induce a cell cycle arrest, allowing damage repair, or to induce apoptosis,” the team further stated.

Chinese scientists have found that a common treatment wakes up dormant cancer cells, causing the deadly disease to spread from the original sites to other organs.

Trilaciclib significantly reduced chemotherapy-induced myelosuppression (CIM) in patients with extensive-stage small cell lung cancer (SCLC), according to a pooled analysis published in Cancer ...

Researchers find that disrupted circadian rhythms may impair gut regeneration and microbiome balance, heightening colon ...

Chemotherapy drugs can treat small cell lung cancer (SCLC), such as cisplatin or etoposide. SCLC is aggressive, but chemotherapy can improve the outlook for many people. Chemotherapy drugs are ...

Tarlatamab, a bispecific delta-like ligand 3–directed T-cell engager immunotherapy, received accelerated approval for the treatment of patients with previously treated small-cell lung cancer.