Objective The significance of pulmonary hypertension (PHT) complicating aortic stenosis (AS) is poorly characterised. In a large cohort of adults with at least moderate AS, we aimed to describe the ...

Learn more about current thinking regarding COPD and find out how three different mechanisms of airflow obstruction play a role in COPD pathogenesis.

The current pathophysiology of COPD encompasses three main characteristics: emphysema, chronic bronchitis and small airway disease. Macrophages and neutrophils are implicated in this process; thus ...

Pulmonary hypertension due to left heart disease (PH-LHD) is the most common type of pulmonary hypertension, although an accurate prevalence is challenging. PH-LHD includes PH due to systolic or ...

Clinical and microbial epidemiology studies of CF pulmonary exacerbations continue to provide important insight into the course, prognosis and complications of the disease. This review provides a ...