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Mice taught to link smells with tastes, and later fear, revealed how the amygdala teams up with cortical regions to let the ...
A new study published in the journal Molecular Psychiatry provides initial evidence for a non-invasive brain stimulation ...
Our brain makes decisions based on direct associations between stimuli in our environment, but it often also does so based on ...
Abstract Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD Post-traumatic stress disorder (PTSD) is a polygenic disorder occurring after extreme trauma exposure. Recent ...
The human brain is made up of billions of interconnected cells that are constantly talking to each other. A new Nature study zooms in to the single-cell level to see how this cellular communication ...
More information: Ahyeon Hwang et al, Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD, Nature (2025). DOI: 10.1038/s41586-025-09083-y ...
The authors first sequenced RNA from nuclei in post-mortem brain samples from 111 individuals with and without PTSD, producing the most extensive molecular profiling yet for this kind of tissue.
Summary: Childhood trauma doesn’t just leave psychological scars—it biologically reshapes the brain through chronic neuroinflammation and structural changes, increasing vulnerability to psychiatric ...
ABSTRACT: This paper revisits the relations between trauma, repression, foreclosure, and neurodevelopmental disorders from a longitudinal perspective. We propose that failures in symbolization, a ...
Kuldeep Shrivastava et al, Energy state guides reward seeking via an extended amygdala to lateral hypothalamus pathway, Nature Communications (2025). DOI: 10.1038/s41467-025-59686-2 ...