Getting drugs to the brain is difficult. The very thing designed to protect the brain's environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from ...

The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function.

To recreate the barrier, the research team took those cell types that naturally make up the blood-brain barrier – microvascular endothelial cells, human astrocytes and human pericytes – and combined ...

By getting drugs beyond the blood-brain barrier, researchers believe they could better target treatment for Alzheimer’s disease, seizures, and plenty more. So, it’s safe to say it’s been a goal.

The blood-brain barrier is a protective layer that limits which molecules can access our gray matter. “That is very important to protect the brain, but also it makes it really hard when you do ...

Weizmann Institute scientists have discovered two small molecules that can cross the blood-brain barrier in mice, slowing and even reversing the effects of Huntington's, which is incurable.

Huang Q, et al. Targeting AAV vectors to the central nervous system by engineering capsid–receptor interactions that enable crossing of the blood–brain barrier. PLoS Biol. 2023;21(7):e3002112. Shay TF ...

Scientists have long struggled to define brain fog—let alone pinpoint a cause for it. But research is starting to reveal multiple potential causes from inflammation to a leaky blood-brain barrier.

Scientists Find Way to Deliver Medicines Across Brain's Protective Barrier By Dennis Thompson HealthDay Reporter WEDNESDAY, Nov. 27, 2024 (HealthDay News) -- The blood-brain barrier is a natural ...

Maybe the blood brain barrier disruption seen in some concussion patients applies to long COVID brain fog, too, the researchers surmised. Evidence for SARS-CoV-2’s damaging effects on the brain ...

This is also the first study that shows how quickly the blood-brain barrier closes after being opened by the ultrasound. It closes in the first 30 to 60 minutes after the communication. and this ...