High Blood Pressure Has the Biggest Impact on Brain Health as We Age When assessing the 17 modifiable risk factors, high blood pressure (hypertension) emerged as the one with the biggest impact.

Nanobiotechnology-Based Strategies for Crossing the Blood–Brain Barrier Kewal K Jain Disclosures Nanomedicine. 2012;7 (8):1225-1233.

Neurizon’s lead drug crosses blood-brain barrier, reinforcing ALS treatment potential Neurizon reports encouraging new rodent preclinical pharmacokinetic data for its lead candidate NUZ-001 ...

Blood-Brain Barrier Penetration In the PK study NUZ-001 and its major active metabolite NUZ-001 Sulfone successfully crossed BBB, a key challenge for therapies targeting brain diseases.

Neurodegenerative diseases have always posed a significant therapeutic challenge due to the restrictive nature of the blood–brain barrier (BBB). Intranasal drug delivery has emerged as a noninvasive ...

This cover image depicts a human brain with colorful microplastic particles scattered across its surface, juxtaposed with a white plastic spoon as a visual representation. Research has revealed that ...

Collaboration will leverage Key2Brain’s technology to develop blood-brain barrier-crossing enzyme replacement therapies for lysosomal storage disorders Agreement is built on a partnership initiated ...

We have evaluated a novel in vitro cell-based human blood−brain barrier (BBB) model that could predict in vivo human brain penetration for compounds with different BBB permeabilities using the ...

Collaboration will leverage Key2Brain’s technology to develop blood-brain barrier-crossing enzyme replacement therapies for lysosomal storage disorders June 11, 2025 4 min read ...

What’s the Right Dose? For anything to enter the brain, it must cross the blood-brain barrier, a tight network that safeguards the brain. Studies show that creatine can cross that barrier, but only ...