Blood-Brain Barrier Penetration In the PK study NUZ-001 and its major active metabolite NUZ-001 Sulfone successfully crossed BBB, a key challenge for therapies targeting brain diseases.

Changes in blood–brain barrier (BBB) properties and endocannabinoid system function contribute to stress responses and have been implicated in the development of mood disorders. Here, we report ...

Neurizon’s lead drug crosses blood-brain barrier, reinforcing ALS treatment potential Neurizon reports encouraging new rodent preclinical pharmacokinetic data for its lead candidate NUZ-001 ...

Collaboration will leverage Key2Brain’s technology to develop blood-brain barrier-crossing enzyme replacement therapies for lysosomal storage disorders June 11, 2025 4 min read ...

Brain swelling, or cerebral edema, is a medical emergency. Learn about the evidence-based treatments doctors use to reduce ...

Collaboration will leverage Key2Brain’s technology to develop blood-brain barrier-crossing enzyme replacement therapies for lysosomal storage disorders Agreement is built on a partnership ...

The Blood-Brain Barrier Summit will take place online from June 28-30, 2021. This Hanson Wade event is aimed at experts looking to deliver CNS drug candidates safely and successfully across the ...

High Blood Pressure Has the Biggest Impact on Brain Health as We Age When assessing the 17 modifiable risk factors, high blood pressure (hypertension) emerged as the one with the biggest impact.

Nanobiotechnology-Based Strategies for Crossing the Blood–Brain Barrier Kewal K Jain Disclosures Nanomedicine. 2012;7 (8):1225-1233.

Bexorg’s whole-brain discovery platform is the only technology capable of perfusing isolated, cadaver human and pig brains with custom-made artificial blood, thereby restoring metabolic and ...

New research analyzed brain imaging information with clinical evaluation to derive six brain-based psychopathology dimensions ...