Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid ...

Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid ...

This study identifies astrocyte-intrinsic mechanisms by which the LRRK2 G2019S, a mutation linked to familial Parkinson's disease, disrupts synaptic integrity in the anterior cingulate cortex. The ...

Emerging research suggests that a daily coffee habit may contribute to longevity and improved aging. Beyond alertness, ...

Highly prized agarwood, used in medicine, is rare. New research shows that growing high-quality agarwood sustainably requires ...

Neuronal AMP-activated protein kinase modulates this process, the authors found. Knocking it out exacerbated lipid droplets in the glia, while activating the kinase alleviated them. However, it’s ...

Smoothened/AMP-Activated Protein Kinase Signaling in Oligodendroglial Cell Maturation Alice Del Giovane 1 Mariagiovanna Russo 2 Linda Tirou 2 Hélène Faure 2 Martial Ruat 2 Sonia Balestri 1 Carola ...

Background: AMP-activated protein kinase (AMPK) is a therapeutic target against type II diabetes (T2D). Synthetic sesquiterpene derivatives were investigated to identify novel AMPK activators as ...

Sirtuin 1 Activation Contributes to Sal A-Induced AMP-Activated Protein Kinase Activation and Uncoupling Protein 1 Upregulation Both AMPK and SIRT1 activation improved thermogenic program in ...

AMP-activated protein kinase (AMPK) is an important energy sensor located in cells throughout the human body. From the periphery, AMPK is known to be a metabolic master switch controlling the use of ...

The AMP-activated protein kinase (AMPK) is a key regulator of cellular and whole-body energy homeostasis, which acts to restore energy homoeostasis whenever cellular energy charge is depleted. Over ...