Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

Most neurons that carry signals regarding movement and higher-level functions, such as thinking and reading, are myelinated. Neurons that control feelings of pain and temperature are sometimes ...

They contract and relax automatically and receive signals from the autonomic nervous system, which regulates your internal bodily functions ... divided into myofibrils that contain thick (myosin) and ...

Department of Respiratory and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, Institute of Respiratory Health, Frontiers Science Center for Disease-related ...

Your first instinct is to pull your head toward your shoulder, trying to lengthen your stiff, sore muscles. We’ve all been told stretching is a great way to keep your body loose and limber, and ward ...

Primary immunodeficiencies are diseases in which part of the body's immune system is missing or does not function properly ... the role of the evolutionary conserved WASp family of actin regulators ...

Introduction: Myosin proteins interact with filamentous actin and translate the chemical energy generated by ATP hydrolysis into a wide variety of mechanical functions in all cell types. The classic ...

These findings suggest that RhoA and ROCK may couple or coordinate the dynamics of actomyosin network with the dynamics of mitochondrial network to achieve optimal actin and myosin function, leading ...