Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

Phospho-Deficient and Depletion of CAV-1 Compromises the Assembly of Contractile Stress Fibers by Deactivating RhoA-Dependent Myosin ... cortical actin filaments and membrane-located mechanosensitive ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

Evidence for a final common pathway for disorders of the myocardium (pages 246 and 320–330). These studies further our understanding of the heart in health and disease, particularly in the ...

They can be hereditary or acquired conditions. Long QT syndrome type 3 gain-of-function of Na v 1.5 increases ventricular fibroblasts proliferation and pro-fibrotic factors The Scn5a-ΔQKP mouse ...

They have specific roles in the organism of which they are part. Their structure is adapted to their function. They are often grouped together with other similar cells in tissues. Root hair cell ...

Reduction in QD fluorescent intensity correlates with greater heat loss, reflecting inefficient myosin function (less mechanical work performed and more heat loss on ATP hydrolysis by myosin). A ...

The skin is the largest and heaviest organ of the body. To function as a protective barrier, it must cover the entire outside of the body, from the top of a person’s head to the end of the toes. The ...

Most neurons that carry signals regarding movement and higher-level functions, such as thinking and reading, are myelinated. Neurons that control feelings of pain and temperature are sometimes ...

Unconventional Computing Laboratory, University of the West of England, Bristol BS16 1QY, U.K.