Filopodia help cells move but also aid cancer spread. Scientists have revealed how fascin proteins build these structures, ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

However, most animal cells have complex morphologies because the membrane adheres strongly to the cytoskeleton. In animal cells, movement of membrane into an endocytic vesicle or lamellipodium ...

1 function, there is an initial delay in ISV formation during ... cytoplasmic viscosity and increase spacing between the plasma membrane and the underlying actin cytoskeleton, promoting actin monomer ...

A degree of cytoskeleton enrichment should be established in each study by determining the ratio of actin, tubulin or other ... is involved in all main functions of immune cells related to the ...

"Going forward, hopefully we've made it easier to study these protein networks, where function emerges at the level of thousands of molecules." Alushin's lab specializes in understanding the ...

suggesting a contribution of altered cytoskeleton organization in PCDH19-CE pathogenesis in the control of cell division and differentiation. Here, we evaluate the consequences of altered PCDH19 ...

Actin filaments are composed of two intertwined ... proteome can vastly contribute to our understanding of cytoskeleton composition, function, regulation and dynamics. The opportunity to use ...