The chirality of tissues and organs is essential for their proper function and development. Tissue-level chirality derives from the chirality of individual cells that comprise the tissue, and cellular ...

The cytoskeleton is a cellular scaffolding system whose functions include maintenance of cellular shape, enabling cellular migration, division, intracellular transport, signaling and membrane ...

One of the best-studied functions of immune cells in which cytoskeletal elements play a key role is phagocytosis. The function of the phagosome skeleton is to give structure to a phagosome and to ...

Studies have found that aging alters actin expression, disrupting the cytoskeleton’s functions, which can lead to age-related diseases, including cancer and neurodegenerative diseases.

Actin can be found in two forms, monomeric (G-actin) and filamentous (F-actin). The latter forms filaments that are essential for maintaining cell structure and many other functions.

Cells, the fundamental building blocks of life, are constantly subjected to a variety of mechanical forces within our bodies.

News Release 28-Aug-2024 The functions of actin-binding proteins are regulated by the flexibility and specific helical twists of actin filaments Peer-Reviewed Publication ...

Plasma membrane repair is a fundamental homeostatic process of eukaryotic cells. Here, we report a new function for the conserved cytoskeletal proteins known as septins in the repair of cells ...

Since the molecular machinery governing actin dynamics, polymerization, depolymerization, and rearrangement have been recently described in several excellent reviews (Rottner et al., 2017; Schaks et ...

CHRFAM7A modifies the actin cytoskeleton to a more dynamic and stiffness resistant state in an α7nAChR dependent manner. CHRFAM7A may facilitate neuronal adaptation to changes in the brain environment ...

FLNs are large, homodimeric actin-binding and crosslinking proteins that play a crucial role in connecting the cytoskeleton and plasma membrane, which is important for cardiac development and function ...