It is tempting to see abuse-deterrent opioids as a powerful and singular solution that might go a long way toward addressing our nation’s opioid crisis. But, it is not so simple.

Two reasons why it's too soon to mandate the use of abuse-deterrent opioids: There's no evidence that they work, and they are 10-20 times more expensive.

While there is value in abuse-deterrent formulations of opioid pain medications, ADFs are not intended to be a stand-alone solution to abuse.

Even with abuse-deterrent properties, which attempt to prevent users from crushing or dissolving the drug, opioids can still be abused by patients if they’re swallowed whole. The FDA has not ...

Are Abuse-Deterrent Drugs Less Addictive? Medscape: In a national survey [1] of internists, family physicians, and general practitioners, nearly one half stated that they believed abuse-deterrent ...

Winegarden's study found that an abuse-deterrent formulation can reduce the abuse of opioids by 18% among Medicaid patients and 23% for commercially insured patients. According to Winegarden, who ...

Abuse-Deterrent Opioids — Evaluation and Labeling Guidance for Industry identifies seven current categories for ADFs: Physical/chemical barriers – Physical barriers can prevent chewing ...

Opinion Abuse-deterrent opioids cross an ethical line Subscribers are entitled to 10 gift sharing articles each month. These can be shared with friends and family who are not subscribers.

PALM BEACH, Fla., June 18, 2025 (GLOBE NEWSWIRE) -- FN Media Group News Commentary - The market for abuse-deterrent opioids is still developing, but it's estimated that replacing extended-release ...

Because opioid medications must in the end be able to deliver the opioid to the patient, there will probably always be potential for abuse of these products.

PALM BEACH, Fla., June 18, 2025 (GLOBE NEWSWIRE) -- FN Media Group News Commentary - The market for abuse-deterrent opioids is still developing, but it's estimated that replacing extended-release ...