In a recent study, Associate Professor Makoto Ikeya (Department of Clinical Application) and his team of researchers ...

In 3D cell culture, rather than growing as a layer, cells are cultured in a three-dimensional shape in a gel matrix, or in the form of spheroids or organoids. 3D cultures can be used as model systems ...

More information: Immortalization of patient-derived lip cells for establishing 3D lip models, Frontiers in Cell and Developmental Biology (2024). DOI: 10.3389/fcell.2024.1449224. Provided by ...

Pairing 3D models with translational endpoints. High-content imaging (HCI) is a high-resolution platform originally developed for automated imaging and analysis of 2D cell–based assays.

Integrated protocols and live-cell analysis solutions for different 3D tumor models In the search for greater clinical translation, cancer researchers are increasingly turning to more complex ...

Analysis of 3D Cell Culture Models September 14, 2015. By Brad Larson . September 15, 2015 (Vol. 35, No. 16) Enabling Phenotypic and Target-Based Assay of 3D Cellular Structures. Cancer, the ...

We empower researchers and pharmaceutical companies to explore cell behaviors and treatments in environments that mimic the human body. Our platform integrates cutting-edge 3D cell model architectures ...

Organotypic three-dimensional (3D) cell culture models are becoming more widely used in infectious-disease research, as they mimic the 3D architecture ofin vivotissues more faithfully than ...

By employing 3D cell culture models (i.e. spheroids, organoids), which better recapitulate the native tissue environment in comparison to traditional 2D cultures, disease states can be mimicked more ...

In addition to readouts on cell viability, the Cell Painting assay was adapted for the 3D tumor model. These tumoroids were formed from primary cells isolated from a patient-derived tumor explant ...

Monocytes, B cells, and T cells readily squeezed through the microchannels. While T cells and monocytes infiltrated AD cultures more than they did control cultures, the opposite was true of B cells, ...

As researchers explore therapeutic strategies for more complex and heterogeneous diseases the need for more physiologically relevant models has never been greater. Researchers are increasingly looking ...