The findings reveal how the absence of TRMT10A leads to a reduction in specific transfer RNA (tRNA) levels, disrupting protein synthesis in the brain and impairing synaptic structure and function.

Despite rapid progress in the past few years on our knowledge of RNase Z function in precursor ... and the recent resolution of the structure of RNase Z in complex with tRNA has provided a ...

The tertiary structure of tRNA from yeast has been determined by x-ray diffraction. For maintaining this structure, a basic prerequisite for its cellular function, the repulsive electric force ...

(Image: Public domain, via Wikimedia Commons ... a more comprehensive understanding of the complex interplay between RNA modifications, structure, and function. This knowledge will not only deepen our ...