Frontiers12d
Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation
Acetyl-CoA synthetase (ACS) is one of several enzymes that generate the key metabolic intermediate, acetyl-CoA. In microbes and mammals ACS activity is regulated by the post-translational acetylation ...
Frontiers12d
A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study
Objectives: The objective of this study was to profile the transcriptional profiles of peripheral blood mononuclear cells (PBMCs) and their immune repertoires affected by anti-synthetase syndrome (ASS ...
C&EN11d
Substrate-Induced Dynamic Regulation of the Catalytic Loop in Assisting Allosteric Communication in Formylglycinamidine Synthetase
Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India ...
The EMBO Journal11d
SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation
SLC25A1 drives citrate export from the mitochondria to the cytosol, where it fuels acetyl-CoA synthesis by ATP citrate lyase (ACLY). This acetyl-CoA supply sustains FSP1 acetylation and prevents its ...
C&EN25d
Engineering of Silkworm Tyrosyl-tRNA Synthetase Variants to Create Halogenated Silk Fiber with Improved Thermal Stability
Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), 1-2 Owashi, Tsukuba, Ibaraki 305-8634, Japan ...