Tridecanoic acid (C13) is a rare, odd-chain saturated fatty acid produced mainly by gut and rumen microbes, entering ...

In the biosynthesis of many macrocyclic natural products by multidomain megasynthases, a carboxy-terminal thioesterase (TE) domain is involved in cyclization and product release1,2; however, it ...

A key component of the TCA cycle, a series of reactions that occurs in energy-generating organelles called mitochondria, can dictate the fate of intestinal stem cells.

The CoA based its decision on the fact that the trial judge had failed to take into account the importance of viewing the trademark from different angles. “I struggle with the Supreme Court’s decision ...

The Commission on Audit (CoA), the Supreme Audit Institution (SAI) of the Philippines, led the 2025 Annual Meeting of the International Organization of Supreme Audit Institutions (INTOSAI) Working ...

As explained in an in-depth review, this inactivation stops your body from converting homocysteine into methionine or methylmalonyl-CoA to succinyl-CoA, which are essential for producing and ...

Yersiniabactin (Ybt) synthetase is a three-subunit, 17-domain [7 domains in high molecular weight protein (HMWP)2, 9 in HMWP1, and 1 in YbtE] enzyme producing the virulence-conferring siderophore ...

Post-translational modifications are an essential process for proper protein function and localization. In particular, lipid modification plays a crucial role in the spatial regulation of proteins ...

Aminoacyl-tRNA synthetases (ARSs) enhance the fidelity of protein synthesis through multiple mechanisms, including hydrolysis of the adenylate and cleavage of misacylated tRNA. Alanyl-tRNA synthetase ...