These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

imageimageThere are no cellular or molecular biomarkers diagnostic of myalgic encephalomyelitis (also known as chronic fatigue syndrome [ME/CFS]). We find hundreds of blood-based traits are different, ...

Immuno-Metabolic Mechanisms of Atherosclerosis (2020) Atherosclerosis remains a leading cause of death worldwide, characterised by plaque build-up in artery walls. Dysregulation of lipid homeostasis ...

imageimageEnzyme kinetic data from the BRENDA database were mapped onto the genome-scale metabolic model of Saccharomyces cerevisiae to construct the cell-intrinsic activation interactions network.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. I spent the winters of my youth traveling ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This study presents and characterizes a Dnmt3a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Centrosomes are tubulin-based organelles that ...

imageimageThis study shows that S100PBP interacts with the nucleoporin TPR and regulates meiotic crossover in mice, suggesting potential regulatory roles of nuclear pores in mammalian meiotic ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Studying the human immune system in vivo is ...

imageimageThe balance between cellular energy demand, expenditure, and anabolic processes to meet cells fundamental requirements remains debated. Using integrated temporal metabolomics and lipidomics, ...

How loss of KIF4A chromokinesin reduces chromosome association of condensin has remained unclear. This study demonstrates that human condensin I is auto-inhibited by short linear motifs (SLiMs) in its ...