Scientists at Johns Hopkins Medicine say they have discovered how a group of proteins linked to Parkinson's disease and ...

Previous mouse studies have shown that, when conditions in cells are normal, removing, or “knocking out,” any one of the ...

Fritz Lipmann Institute (FLI) in Jena have discovered a new function of the DNA repair protein ATR in regulating ...

WFS1 and CISD2 regulate IP3R activity through their interaction. In Wolfram syndrome, their dysfunction reduces cytosolic ...

The discovery of the new function of ATR in mitophagy provides insights into the physiological function of a DNA damage response regulator in neuropathies and tissue declines, as well as the aging ...

A project led by scientists at the University of Dundee’s School of Life Sciences and School of Medicine has been selected for the 2025 SPARK NS Translational award, aimed at accelerating scientific d ...

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

Are there key genes involved in TKI resistance in ccRCC? What mechanisms are associated with this development? A research team, led by Professor Ben Liu from the Department of Urology at the First ...

Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...

Scientists have made a potentially "life-changing" discovery that could lead to new drugs for treating Parkinson's disease.

Experts have known for several decades that the PINK1 protein is directly linked to Parkinson’s disease – the fastest growing ...

Speaking to the Walter and Eliza Hall Institute of Medical Research, the study’s author Professor David Komander said: “Our ...