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How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals ...
Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...
Docking of the simulated duplex models on to the argonaute protein gives a direct indication that in the siRNA−mRNA structure, the scissile phosphate of the mRNA strand is more accessible to the ...
Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered ...
Messenger RNA (mRNA) vaccine technology, which rose to prominence during the Covid-19 pandemic, is now being repurposed by South African scientists to tackle one of the world’s oldest ...
Yet, the remaining challenge toward optimizing PM-based mRNA delivery systems for systemic application is to build a functionality to prevent RNase invasion into the polyplex core storing cargo mRNA.
Using capillary gel electrophoresis, researchers from the National Institute of Health Sciences in Kanagawa, Japan studied the factors that optimize chain-length distribution analysis of messenger RNA ...
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