Although intervention strategies targeting lipid metabolism (such as the fatty acid synthase inhibitor TVB-2640) have shown potential in clinical trials, their efficacy is limited by tumor ...

Hymeglusin (1) is a fungal polyketide consisting of a β-lactone ring with a unique (3R,4R) configuration. 1 is a potent 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase inhibitor. Because it ...

The aim of this study was to investigate the influence of PFOA/PFOS on the absorption of fatty acids in the intestine and the underlying mechanisms using three-dimensional (3D) intestinal organoids.

Signal peptidases are essential for protein secretion in all bacteria. In Staphylococcus aureus, the signal peptidase SpsB also cleaves lipoteichoic acid synthase (LtaS), which assembles the essential ...

Both omega-3 and omega-6 polyunsaturated fatty acids (PUFAs) may increase levels of some inflammatory biomarkers associated with increased cardiovascular risk, a new study has found.