Discover how bitter taste receptors in the intestines affect aging. A new study identifies specific receptors linked to metabolic changes, inflammation, and lipid metabolism. Learn how these ...

Get Instant Summarized Text (Gist) A novel GPS NMR method enabled precise tracking of motions within the β 1-adrenergic GPCR, revealing that the receptor exists in a dynamic equilibrium among ...

Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered ...

Timing and Outcomes of Palliative Care Integration Into Care of Adolescents and Young Adults With Advanced Cancer The advent of next-generation antibody-drug conjugates (ADCs), particularly ...

Palatin Technologies, Inc. (NYSE American: PTN), a biopharmaceutical company advancing innovative treatments targeting the melanocortin receptor system, today announced new preclinical data for ...

Traditional SLT involves using a laser to manipulate the eye's trabecular meshwork, located around the base of the cornea, which acts as the natural drain for the eyeball's aqueous humor. Glaucoma is ...

Although TRPV4‐driven RhoA signaling activation has been observed in fibroblasts and trabecular meshwork cells, its role in VICs remains unexplored in the context of AVS. Activation of RhoA signaling ...

The breakthrough, appearing in Nature on Nov. 14, revolves around engineered receptors on the surface of cells that can sense molecules in the surrounding environment and, in response, change the ...

Further, and based on ligand and receptor expression patterns, we document key interactions between SECs and cells of the adjacent trabecular meshwork (TM) drainage tissue. Also, we present cell type ...

2023 Differential roles of FOXC2 in the trabecular meshwork and Schlemm’s canal in glaucomatous pathology Life Sci Alliance 6; 25. Kwon Y. W. et al. 2022 A subset of macrophages and monocytes in the ...

This works by acting on the trabecular meshwork. This refers to spongy tissue in the eye that regulates eye pressure by draining aqueous humor. Generally, people may be able to apply 1 drop in the ...