This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, ...

A new study in Small introduces a modular protein-DNA platform using covalent, site-specific links to create programmable ...

Along with greater accuracy for the prediction of 3D protein structures, it offers a big increase for antibody-antigen interactions and can decipher protein-ligand interactions that – according ...

BACKGROUND: Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of ...

When Alphabet announced in 2021 that its AlphaFold AI could predict the structure of almost every known protein, it was a major story, not just in the pharma world, but beyond. Yet, that was far ...

This can occur either through the influence of imprinted genes on nutrient supply by the placenta 3 or through more specific effects of brain-expressed imprinted genes on brain structure ...