This work also contributes to growing evidence that information beyond the sequence of RNA, such as chemical modifications, can determine the ultimate fate and function of RNA molecules." ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

The discovery of the ribosome and the elucidation of its role in gene expression was one of the main achievements of molecular biology in the 1950s and '60s. Early investigations revealed that ...

it has been challenging to determine whether specific RNA molecules are essential for cell function. “We now have this technology, but the biological question remains: which parts of the ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

Inspired by historical work showing that structure plays a role in the function of other classes of RNA such as transfer ... reveal new clues," Xue says. To determine Braveheart's structure ...

The breadth of functions that RNA performs explains why defective RNA degradation ... Scientists have used cryo-EM microscopy to determine the structure of a key part of the degradation machinery, ...

Instead, genetic surveys of sick people can help determine ... RNA segments from the parent viruses can be mixed and matched like viral Legos. This process can cause rapid shifts in the viral ...

In this article, we define RNA polymerase and further explore its various functions throughout cell biology. RNA polymerase is a multi-unit enzyme that synthesizes RNA molecules from a template of DNA ...

They found that this form of regulation, a chemical modification on RNA called m 6 A ... m 6 A modification plays an important role in the function of the nervous system and in sex determination ...

Ph.D., and his team reveal how the protein SRSF1 possesses the novel function of binding and unfolding complex RNA Guanine-quadruplexes. Present in both DNA and RNA sequences, a G-quadruplex (GQ ...