The implementations of high-throughput genetic technologies, such as oligonucleotide microarrays ... To get as many high-quality sections from one multi-tissue block as possible, it is advisable ...

Paraffin microtomy is performed on routine as well as tissue microarray blocks. The thickness of sections ranges from 3-4 um for both H&E staining and immunohistochemistry. We also perform high ...

Therefore, we investigated the number of sections that are needed to obtain more than 90% of scorable cores from a tissue microarray block. For that purpose, we sectioned one of the two tissue ...

Emphasis on Potential Clinical Applications and Enhancing RNA Sample Quality Researchers are beginning to look at tissue microarrays ... fixed, paraffin-embedded (FFPE) tissue section to a ...

Tissue microarrays (TMAs) have become ubiquitous ... Methods that can be applied to whole-tissue sections are applicable to TMAs including DNA-, RNA- and protein-based assessments.

These delicate sections are floated out on a water bath and picked up on a glass slide. Paraffin wax is dissolved from the tissue block by using solvents. Then the tissues are stained with dyes ...

For this, the tissue sample is preserved and subsequently dehydrated and embedded in paraffin blocks. Further on, thin tissue sections of ... This so-called Tissue Microarray (TMA) is a tissue ...

Each tissue microarray is constructed from paraffin-embedded (FFPE) tissue blocks from a specific number of donor cases ... 22 Cores (Catalog # CSCT001) consist of various sections of artery tissue ...

Histological examination is considered the gold standard for detection, diagnosis and characterization of many clinical conditions, and producing suitable sections for microscopic examination ...

Formalin-Fixed Paraffin Embedded (FFPE ... extensive inventory of pathologist-reviewed FFPE tissue blocks, slides, curls, cores, and tissue microarrays from both normal and diseased subjects ...

This is routinely achieved by placing the paraffin blocks on ice, cooling both the tissue and the wax to a similar consistency and swelling the tissue to make it easier to section. As the block ...

All patient cases underwent a centralized review to determine tumor content (reported as percentage of total cell number) and select the area of the paraffin block for tissue microarray (TMA) ...