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another group identified a gene associated with T1D autoimmunity and deleted this gene. 48 This protected transplanted β cells in a mouse model. Changing Lives, One Cell at a Time At this time, ...
The LIFE-T1D model, demonstrated an ability to estimate the lifetime risk of heart disease among several groups of people with type 1 diabetes (T1D). Researchers have developed a tool they say can ...
TXNIP inhibition has been demonstrated in mouse models and in humans with T1D to protect the body’s own insulin-producing beta cells while promoting overall islet cell health. TIX100 has also ...
A DNA methylation signature outperformed a clinical model at identifying individuals with type 1 diabetes (T1D) who risked progressing to end-stage kidney disease. Researchers measured DNA ...
The finding, published in Diabetes Care, provides the basis for the first evidence-based kidney screening model for people with T1D. Current CKD screening recommendations include annual urinary ...
Our model, which will be made available open-source, will make data on the burden of T1D widely accessible and serve as a platform for stakeholders to make improvements in T1D care and outcomes ...