Ultrasound localization microscopy has enabled super-resolution vascular imaging through precise localization of individual ultrasound contrast agents (microbubbles) across numerous imaging frames.

Schmidt et al. describe an improved version of scanning stimulated emission depletion (STED) fluorescence microscopy to achieve isotropic super-resolution 3D imaging 1.

Three-dimensional (3D) imaging is essential for investigating cellular structure and dynamics. Traditional optical methods ...

When the COVID-19 pandemic swept across the world in 2020, the mRNA vaccines came to the rescue of many people—but in the ...

To avoid this restriction, which is known as vignetting, Cui explains that the team separated the two lenses and inserted a Keplerian telescope between them. “This ‘telescope-within-a-microscope’ ...

Discover how the new technique of HSMP can help scientists gain insights into the world of biological processes and their ...

Single particle reconstruction has recently emerged in 3D fluorescence microscopy as a powerful technique to improve the axial resolution and the degree of fluorescent labeling. It is based on the ...

Scientists have long used fluorescent dyes—which emit light—to research cell structures and activities. By attaching ...

This important work presents a self-supervised method for the segmentation of 3D cells in fluorescent microscopy images, conveniently packaged as a Napari plugin and tested on an annotated dataset.

Fluorescent labeling of cellular substructures is commonly performed using antibody–organic dye conjugates. Organic dyes do not exhibit ideal optical properties in terms of brightness and ...

However, one of the most significant obstacles to the broader application of super-resolution fluorescence microscopy in catalysis research is the limited availability of suitable probe molecules. (8) ...

A unified national ecosystem is telling its story—and showing its strength—at the world’s most important biotechnology event. The BIO International Convention has opened in Boston, and with it the ...