So far sulfanilamide has had no remarkable effect on diseases produced by bacteria other than the streptococcus, men-ingococcus, pneumococcus, or gonococcus. ¶ Although there have been only ten ...

Only since February 1935 has the drug sulfanilamide been known. In the past three years it has proven so useful as a treatment for "coccus" infections (streptococcus, gonococcus, ...

It appears that with sulfanilamide administration and decreased acid excretion, the disturbance in acid–base balance should result in failure to reabsorb fixed base from the glomerular filtrate.

Original Article from The New England Journal of Medicine — Sulfanilamide: Its Mode of Action and Use in the Treatment of Various Infections ...

The Accidental Poison That Founded the Modern FDA Elixir Sulfanilamide was a breakthrough antibiotic—until it killed more than 100 people. An Object Lesson.

LETHAL LIQUID: In 1937, the S.E. Massengill Company of Bristol, Tennessee, began selling bottles of Elixir Sulfanilamide, a liquid version of a popular antibiotic of the day. But more than 100 people ...

Its modern definition means a clear, sweet-flavored liquid medication. However, the case of Elixir Sulfanilamide, a poisonous formulation that was responsible for over one hundred death, went down in ...

SULFANILAMIDE was the drug everyone had been waiting for, a “magic bullet” that would vanquish the bacteria responsible for all manner of infections, from sore throats to pneumonia.