This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

A new concept of kinetic modules in biochemical networks could revolutionize the understanding of how these networks function ...

Singapore national football coach Tsutomu Ogura is demanding better concentration and work rate from his team, ahead of their "must-win" Asian Cup qualifier against Bangladesh. The Lions have not ...

Pathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective ...

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Moody’s cut the US government’s long-term credit rating from AAA to AA1 late Friday, citing escalating deficits and the increasing burden of refinancing US debt amid elevated interest rates.

Dopamine helps the brain reinforce rewarding behaviors, whereas norepinephrine affects heart rate, blood vessels ... An allergic reaction to Adderall may cause swelling in the tongue, throat ...

Search Engine Land is your premier source for Google SEO news, strategies, and in-depth content. You’ll find a variety of up-to-date and authoritative resources, including the latest news ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Accurately modeling chemical reactions in molecular dynamics simulations requires ...