Iowa State is joining the loaded Players Era Festival in Las Vegas in November. The Cyclones face quality opponents St. John's, Creighton to start.

Newly renamed as Casey's Center, the former Wells Fargo Arena has been making Des Moines memories for 20 years this month. Here's a look back.

In September, UnityPoint Health's John Stoddard Cancer Center will open a new oncology and hematology clinic. DES MOINES, ...

After Des Moines Oktoberfest event organizers moved the event from its Water Works Park location to Ankeny for the foreseeable future, the Des Moines Biergarten announced its own celebration.

Des Moines police arrested 44-year-old Mario Ricardo Campos, who allegedly fled from a deadly crash. Police say Campos was impaired.

DES MOINES, Iowa — Des Moines police are investigating after a body was recovered from the Des Moines River Friday night.

Nitrate levels remain elevated in the Des Moines and Raccoon rivers, two of the drinking water sources for Central Iowa Water Works' 600,000 customers. The regional utility recently shared how it ...

Modeled partly on the Dickeyville Grotto, Madeline Buol spent 15 years building a backyard shrine that is now on view at the John Michael Kohler Arts Center.

As Iowa Christian faith leaders are preparing for the impact President Trump’s “one big, beautiful bill act” will have on ...

Offseason winner? Iowa basketball makes a case. How Ben McCollum got it done. Tyler Tachman Des Moines Register 0:04 11:03 ...