1 pM), consistent with its proposed mechanism of action as an inhibitor of signal transduction, and growth-inhibited cells were arrested in G 1 (Gibbons et al., 2000). In studies involving ...

This diversity may be crucial for the specificity in the signal transduction process, by ensuring the formation of the proper signalling complex among the many TLRs and IL-1Rs. The interactions ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.