This diversity may be crucial for the specificity in the signal transduction process, by ensuring the formation of the proper signalling complex among the many TLRs and IL-1Rs. The interactions ...

To complement these single-protein assays, protein-protein interactions within signal transduction pathways show great promise as a new class of biomarker. Such interaction-based markers could be ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...