Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are ...

The natural protein universe is vast, and yet, going beyond and designing new proteins not observed in nature can yield new ...

Older adults and women using Wegovy for obesity management may be more likely to lose lean mass, although increasing protein intake may help protect against lean mass loss, according to a speaker.

David Baker’s lab has successfully designed binders to disordered proteins, expanding therapeutic access to over 50% of the ...

Further FT-IR experiments to study the secondary protein structure of BSA revealed varied results. The amount of β-sheet structures in BSA increased with longer stirring times in the presence of ...

The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of ...

While unconditional protein generation, as well as protein motif scaffolding are fairly standard for current protein structure generators, salad reaches larger proteins up to 1,000 amino acids and can ...

Protein secondary structure prediction is a pivotal task in computational biology, essential for understanding protein folding and function. This study evaluates the efficacy of three models—K-Nearest ...

Researchers from UC Berkeley and UCSF introduce ProteinZen, a two-stage generative framework that combines flow matching for backbone frames with latent space modeling to achieve precise all-atom ...

Abstract Although the αC-β4 loop is a stable feature of all protein kinases, the importance of this motif as a conserved element of secondary structure, as well as its links to the hydrophobic ...

David Baker, Demis Hassabis and John Jumper shared the Nobel prize in chemistry for work that revolutionized our understanding of protein structure.