Understanding human biology requires more than mapping our genes—we must also understand how gene expression is regulated to ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

AI is being used to model gene regulation and predict cellular behavior from transcriptomic data. Learn how these tools aid ...

Further advances in the genetic analysis of variation in gene expression will contribute to our understanding of transcriptional regulation and will provide models for studying other quantitative ...

Background Current treatments with tyrosine kinase inhibitors and immune checkpoint inhibitors have limited efficacy for hepatocellular carcinoma (HCC) due to drug resistance. Emerging therapies such ...

Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA ...

Small RNA molecules, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), are critical regulators that orchestrate ...

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...

The three-dimensional (3D) chromatin structure of Epstein–Barr virus (EBV) within host cells and the underlying mechanisms of chromatin interaction and gene ... expression of genes crucial for host ...

Exposure to alcohol during the first weeks of embryonic development changes gene activity and cellular metabolism. In ...

Synthetic chemicals and plastics are useful and indispensable in our lives. On the other hand, the world is grappling with ...