Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and ...

Vitamin D deficiency directly causes erectile dysfunction by increasing superoxide and reducing protective SLPI levels, as ...

A new study identifies a blood-based biomarker that detects pre-symptomatic Parkinson’s disease by measuring the ratio of ...

RNA therapeutics have existed since the late 90s but have only come into focus in the last few years. This renewed interest has largely been attributed to the success of messenger RNA (mRNA) vaccines ...

SINGAPORE – A new programme has been launched in Singapore to formally study the applications of ribonucleic acid (RNA) in vaccine development, as well as in disease therapy and prevention ...

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m 6 A, plays a critical role in the ...

The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting hepatic synthesis ... occurred in 35 participants. Dose-dependent, generally mild injection-site ...

Ribonucleic acid (RNA) plays a central role in the implementation of genetic information. RNA interference (RNAi) acts like a "gene switch," selectively silencing specific genes. It uses ...

In the default model, the graph representing each individual enhancer can be arbitrarily complicated. To show how the ABC Score formula can arise from the default model, we need to impose the further ...