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From sequence to structure: A fast track for RNA modelingIn Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...
Negotiating the twists and turns of RNA promises to become easier, thanks to new techniques such as in-gel analysis, sequencing, mapping, and nanoassembly.
Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.
The groups analyzed the AF647-labeled RNA using a microscopy technique called TRAST (TRAnsient STate) monitoring to detect this fluorescence blinking in real time.
RNA Timeline: A History in Hybridization and Structure RNA Timeline: A History in Hybridization and Structure Alexander Rich and David Davies discover the double-stranded RNA helix and show that ...
Before RNA and after : geophysical and geochemical constraints on molecular evolution / Stephen J. Mojzsis, Ramanarayanan Krishnamurthy, and Gustaf Arrhenius -- Prospects for understanding the origin ...
Evidence suggests that RNA aids nucleation of these pathological aggregates; however, the mechanism has not been investigated at the level of atomic structure. Here, we present the 3.4-Å resolution ...
Google DeepMind launches AlphaFold 3, the next generation of its molecular structure prediction model that can aid drug discovery and other molecular developments.
Inching Closer to a Structure Several years ago, Dr. Puno began studying NEXT's structure using the then gold standard approach of X-ray crystallography. In this method, proteins are first made ...
The RNA exosome degrades RNA that is faulty, harmful, or no longer needed. Scientists have used cryo-EM microscopy to determine the structure of a key part of the degradation machinery, called NEXT.
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