TFIID enables RNA polymerase II promoter-proximal pausing. Mol Cell 2020, 78: 785 – 793. Schier, AC; Taatjes, DJ. Structure and mechanism of the RNA polymerase II transcription machinery. Genes Dev.

An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. This image was created by reconstructing X-ray diffraction crystallography ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Chromatin structure allows activators to associate ... result of TFs that govern the way genes are transcribed and RNA polymerase II is recruited. Through these mechanisms, TFs control important ...