The pervasiveness of RNA synthesis in eukaryotes is largely the result of RNA polymerase II (Pol II)-mediated transcription, and termination of its activity is necessary to partition the genome ...

How RNA Polymerase II Gets The Go-ahead For Gene Transcription Date: October 9, 2009 Source: Ludwig-Maximilians-Universität München Summary: The central dogma of molecular biology states that ...

Scientists have recently uncovered the mechanisms of how RNA polymerase II performs intrinsic cleavage reaction to proofread RNA transcriptions, shedding light on how misregulation of accurate ...

An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. This image was created by reconstructing X-ray diffraction crystallography ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

For Lucas Farnung, there is no question more fascinating than how a single fertilized egg develops into a fully-functioning human. As a structural biologist, he is studying this process on the ...

The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (RNAPII), governs the expression of all protein-coding and most non-coding ...

DelveInsight’s, “Metastatic Urothelial Carcinoma Pipeline Insight, 2025” report provides comprehensive insights about 40+ ...

This article describes the three types of RNA polymerase (RNAP), the enzyme responsible for transcription in eukaryotic cells.

It started as a home-cooked meal, ended in multiple deaths and a court sentence for Erin Patterson. Here's how the death cap ...

These techniques showed that the herpes virus’ hostile takeover begins within the first hour, with the virus hijacking a key human enzyme – RNA-polymerase II – to synthesise its own proteins. Just ...