Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...

These cells conceal integrated provirus in a transcriptionally silent state, beyond the reach of both immune surveillance and antiretroviral therapy. Researchers at the Peter Doherty Institute in ...

ProvBD (provirus boundary delimiter) is a novel bioinformatics tool that predicts the precise boundaries of proviruses by identifying attL/R sites. - mujiezhang/ProvBD ...

Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

Diseases such as AIDS and cancers may require the introduction of multiple genes into either stem cells or nondividing cells, among others, for therapeutic purposes. Such genes may act at ...

Four new sesterterpenoids, ansellone B (4), phorbadione (5), secoepoxyansellone A (6), and alotaketal C (7), have been isolated from specimens of the sponge Phorbas sp. collected in British Columbia.