"These findings open new possibilities for protein-ligand complex modeling, indicating significant potential for ProteinReDiff in various biotechnological and pharmaceutical applications." ...

Monitoring protein-ligand interactions is thus essential for characterizing proteins with unknown functions, for investigating regulatory mechanisms in cell metabolism, and for elucidating drug ...

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...

New research uses AI to engineer enzymes with intricate active sites, expanding the possibilities for synthetic biocatalysts.

In biology, the binding of cellular proteins to molecules called ligands produces a myriad of functions essential for life, including cell signaling and enzymatic action. In biotechnology and medicine ...

"These findings open new possibilities for protein-ligand complex modeling, indicating significant potential for ProteinReDiff in various biotechnological and pharmaceutical applications." ...

The ability to alter protein binding can create tailored therapeutics with reduced side effects, sensitive diagnostic tools, targeted drug delivery and sustainable bioremediation. Various approaches ...