Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Antibody drugs have reshaped how we treat diseases. By harnessing the immune system to destroy tumours or temper excessive inflammation in autoimmune disorders, these therapeutics have become ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

We expect Novo to gain $75 billion of a more than $200 billion global GLP-1 market in diabetes and obesity by 2031, ahead of semaglutide's 2032 patent expiration, with Lilly standing as the firm's key ...

As shown in Figure 2A, single-point mutations produced complex results during the combination ... the AI model can not only guide the evolution of protein thermal stability, enzymatic activity, ligand ...

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society by ...

Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each performing a specialized function. Researchers have long known that the ...

Ligand Pharmaceuticals is headquartered less than an hour north of me as the crow flies in Jupiter, FL. Ligand Pharmaceuticals has several products on the market as well as candidates in its ...

Once confined to sportsmen and women, high-protein diets are now commonplace – with Paleo, Atkins, Zone and Dukan advocating that people eat large quantities of fish, meat, eggs, nuts and cheese ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...