CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing.

Gene editing and many other useful biotechnology tools came from studies of bacteria fighting off viral invaders. But ...

As an independent investigator at the National Institutes of Health (NIH)—where she set up shop in 1976—Gottesman made major contributions in the field of prokaryotic gene regulation, uncovering key ...

Horizontal gene transfer (HGT) is the movement of genetic material from one organism to another. In this article, we will discuss what HGT is, how it is used in research, how to detect it and the ...

Edited by Wilfred van der Donk, University of Illinois at Urbana-Champaign, Urbana, IL; received November 27, 2024; accepted February 21, 2025 ...

Here, we investigated soil prokaryotic communities from Chinese northern grasslands on a scale up to 4000 km in both alpine and temperate biotas. Prokaryotic similarities increased over geographic ...

The ICSP is an organization of microbiologists and taxonomy experts who maintain the International Code of Nomenclature for Prokaryotes (ICNP), a set of rules dictating how prokaryotic organisms can ...