While prokaryotic cells do not have membrane-bound structures, they do have distinct cellular regions (Figure 1). In prokaryotic cells, DNA bundles together in a region called the nucleoid. Primitive ...

Isomerase has formed a strategic partnership with BugBiome, which is focused on the discovery of novel targeted ...

More information: Dongying Wu et al, A metagenomic perspective on the microbial prokaryotic genome census, Science Advances (2025). DOI: 10.1126/sciadv.adq2166 ...

CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing.

Isomerase has formed a strategic partnership with fellow Cambridge business BugBiome focused on the discovery of novel targeted bioinsecticides via insect behavioural screening.

Laboratory of Medicinal Chemistry, Department of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano-machi, Hachi-oji, Tokyo 192-0015, Japan ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...