ensuring that alignment methods remain robust in the era of big data. Progressive Alignment: An approach that constructs multiple sequence alignments by iteratively aligning pairs of sequences ...

Alignment of DNA and protein sequences is a basic tool in the study of evolutionary, structural and functional relationship among macromolecules. Present sequence alignment methods are somewhat ...

This approach requires an alignment of the genome sequences ... called Progressive Cactus, which can work for hundreds and even thousands of genomes. "Most previous alignment methods were limited ...