We designed and synthesized seven α-GalCer analogues with a pyrazole moiety and varying positions of a phenyl group in the sphingosine backbone to polarize cytokine secretion. On the basis of in vitro ...

Carboxylic acids are ubiquitous in bioactive organic molecules and readily available chemical building blocks. Carboxylic ...

For more than a century, the well-known 18-electron rule has guided the field of organometallic chemistry. Now, researchers at Okinawa Institute of Science and Technology (OIST), in collaboration with ...