This interaction is likely to permit a degree of cellular signalling integration, as PTEN associates with myosinV, and antagonizes PI(3)K signalling and functions, when GSK3 is active. Consistent ...

In 1979, famed molecular biologist, Francis Crick, stated that it would be "[impossible] to create an exact wiring diagram ... study the relationship between neural structure and function at ...

We propose that RPA1 is a target of PTEN function in fork protection and that PTEN maintains genome stability through regulation of DNA replication. In this study, we demonstrate that PTEN plays ...