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For more than a century, the well-known 18-electron rule has guided the field of organometallic chemistry. Now, researchers at Okinawa Institute of Science and Technology (OIST), in collaboration with ...
An interaction between two proteins points to a molecular basis for memory. But how do memories last when the molecules that ...
We have previously described opioid peptidomimetic, 1, employing a tetrahydroquinoline scaffold and modeled on a series of cyclic tetrapeptide opioid agonists. We have recently described modifications ...
Structure–activity relationship (SAR) studies of numerous opioid ligands have shown that introduction of a methyl or ethyl group on the tertiary amino group at position 17 of the epoxymorphinan ...
News & Views Published: October 2005 Decoding chemical structures from genomes Brian O Bachmann Nature Chemical Biology 1, 244–245 (2005) Cite this article ...