The crystal structure of the RCC1–nucleosome core particle shows pseudo-two-fold symmetry: one RCC1 molecule interacts with each of the two histone faces of the nucleosome ().The RCC1 β ...

Scientists have long known that cells in all eukaryotes, from fish to trees to people, pack DNA in exactly the same way. DNA strands are wound around a ‘hockey puck’ composed of eight histone proteins ...

DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair. An in vitro biochemically defined system has been developed in which six repair factors are sufficient to excise ...

A group including Jonathan Widom at Northwestern University and Eran Segal of the Weizman Institute used sophisticated computer modeling along with experimental approaches to uncover DNA-encoded rules ...