We have examined the abilities of three complementary γ-peptide nucleic acid (γPNA) oligomers to invade an RNA G-quadruplex and potently inhibit translation of a luciferase reporter transcript ...

Technical Report Published: March 2000 Custom fluorescent-nucleotide synthesis as an alternative method for nucleic acid labeling Octavian Henegariu, Patricia Bray-Ward & David C. Ward Nature ...

The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are ...

Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the ...

The NANOSPRESSO system has high potential to enable the point-of-care production of nucleic acid-loaded LNPs, bypassing the logistical and scalability limitations of centralized manufacturing. Its ...

The Food and Drug Administration (FDA, the Agency, or we) is classifying the herpes simplex virus nucleic acid-based assay for central nervous system infections into class II (special controls). The ...

The development of an autocatalytic, exponential replicator that is based solely on nucleic acids has implications for our understanding of the origins of life and potential applications in ...