For example, one study estimated that there are ... Another class of small non-coding RNA is Piwi-interacting RNA (piRNA). piRNAs represent the most abundant class of small non-coding RNA ...

This Review discusses the state of currently available long non-coding RNA annotations and the impact ... This Review considers examples from animals, plants and fungi. MicroRNAs are key ...

Example: Overexpression of miRNA-124 leads to Alzheimer’s-like pathologies in mice, and elevated levels of the miRNA are found in the brains of people who died from the disease. As the name suggests, ...

MicroRNAs, for example, home in on certain protein-coding ... breast epithelial cells -- a good initial sign that the non-coding RNA was associated with cancer development. Those cells were ...

For example, Xist/Tsix is a lnc RNA SAS which controls the X chromosome inactivation. Some of the SAS pairs may also contain coding/non-coding pairs. However, the biological function of most NATs ...

When CHASERR (CHD2 adjacent, suppressive regulatory RNA) is not functioning normally, it leads to the expression of abnormal levels of CHD2 protein. The findings, which highlight the importance of non ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 nucleotides longer than typical RNAs and are widely expressed in cells ...

One such non-coding RNA is 4.5SH, found only in small rodents ... “To our knowledge, this is the first example of a naturally produced RNA that can regulate alternative splicing in a definitive ...

However, studies over the last few years demonstrated that just 1.5% of the 3 billion base pairs of DNA constituting the human genome generate the ~20,000 protein coding genes, whereas at least 90% of ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA ... as key regulators in atherosclerosis. For example, miR-146a/b modulates inflammatory responses by targeting ...